Obesity, cytokines and endothelial dysfunction: A link for the raised cardiovascular risk associated with visceral obesity

被引:26
作者
Esposito, K
Nicoletti, G
Giugliano, D
机构
[1] Univ Naples 2, Ctr Obes Management, Dept Geriatr Metab Dis, Naples, Italy
[2] Univ Naples 2, Chair Plast Surg, Naples, Italy
[3] Univ Naples 2, Cardiovasc Res Ctr, Naples, Italy
关键词
obesity; inflammation; endothelial dysfunction; cytokines; cardiovascular disease;
D O I
10.1007/BF03345092
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:646 / 649
页数:4
相关论文
共 23 条
[1]   Body fat distribution predicts the degree of endothelial dysfunction in uncomplicated obesity [J].
Arcaro, G ;
Zamboni, M ;
Rossi, L ;
Turcato, E ;
Covi, G ;
Armellini, F ;
Bosello, O ;
Lechi, A .
INTERNATIONAL JOURNAL OF OBESITY, 1999, 23 (09) :936-942
[2]   The influences of obesity and glycemic control on endothelial activation in patients with type 2 diabetes [J].
Bagg, W ;
Ferri, C ;
Desideri, G ;
Gamble, G ;
Ockelford, P ;
Braatvedt, GD .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (11) :5491-5497
[3]   Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss [J].
Bastard, JP ;
Jardel, C ;
Bruckert, E ;
Blondy, P ;
Capeau, J ;
Laville, M ;
Vidal, H ;
Hainque, B .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2000, 85 (09) :3338-3342
[4]   Inflammatory cytokines impair endothelium-dependent dilatation in human veins in vivo [J].
Bhagat, K ;
Vallance, P .
CIRCULATION, 1997, 96 (09) :3042-3047
[5]   Early upregulation of endothelial adhesion molecules in obese hypertensive men [J].
Ferri, C ;
Desideri, G ;
Valenti, M ;
Bellini, C ;
Pasin, M ;
Santucci, A ;
De Mattia, G .
HYPERTENSION, 1999, 34 (04) :568-573
[6]   Energy restriction and weight loss on very-low-fat diets reduce C-reactive protein concentrations in obese, healthy women [J].
Heilbronn, LK ;
Noakes, M ;
Clifton, PM .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2001, 21 (06) :968-970
[7]   Obesity as a medical problem [J].
Kopelman, PG .
NATURE, 2000, 404 (6778) :635-643
[8]   INCREASING PREVALENCE OF OVERWEIGHT AMONG US ADULTS - THE NATIONAL-HEALTH AND NUTRITION EXAMINATION SURVEYS, 1960 TO 1991 [J].
KUCZMARSKI, RJ ;
FLEGAL, KM ;
CAMPBELL, SM ;
JOHNSON, CL .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 272 (03) :205-211
[9]   Potential role of TNF-α in the pathogenesis of insulin resistance and type 2 diabetes [J].
Moller, DE .
TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2000, 11 (06) :212-217
[10]   Obesity and body fat distribution induce endothelial dysfunction by oxidative stress - Protective effect of vitamin C [J].
Perticone, F ;
Ceravolo, R ;
Candigliota, M ;
Ventura, G ;
Iacopino, S ;
Sinopoli, F ;
Mattioli, PL .
DIABETES, 2001, 50 (01) :159-165