Pulmonary fibrosis: thinking outside of the lung

被引：47

作者：

Garantziotis, S

Steele, MP

Schwartz, DA

机构：

[1] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA

[2] Durham Dept Vet Affairs Med Ctr, Durham, NC USA

来源：

JOURNAL OF CLINICAL INVESTIGATION | 2004年 / 114卷 / 03期

关键词：

D O I：

10.1172/jci200422497

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Pulmonary fibrosis is a devastating condition that leads to progressive lung destruction and scarring. Previous mechanistic research has focused on the local fibroproliferative process in the lung. However, emerging evidence suggests that circulating cells of hematopoietic origin play a crucial role in the pathogenesis of this disease (see the related article beginning on page 438).

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页码：319 / 321

页数：3

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