Elucidation of the mechanism of chiral selectivity in diastereomeric salt formation using organic solvent nanofiltration

被引：12

作者：

Ghazali, NF ^{[1
]}

Patterson, DA ^{[1
]}

Livingston, AG ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem Engn, London SW7 2BY, England

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 08期

关键词：

D O I：

10.1039/b400982g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Organic solvent nanofiltration (OSN) was used to investigate the mechanism of chiral selectivity in diastereomeric salt formation of alpha-phenylethylamine with D-tartaric acid and di-p-toluoyl-D-tartaric acid as resolving agents; results indicate that for these systems chiral selectivity occurs only upon crystallisation and chiral interactions in solution were negligible.

引用

页码：962 / 963

页数：2

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