Diffusion tensor imaging in refractory epilepsy

被引:85
作者
Rugg-Gunn, FJ
Eriksson, SH
Symms, MR
Barker, GJ
Thom, M
Harkness, W
Duncan, JS
机构
[1] Natl Soc Epilepsy & Res, MRI Unit, Dept Clin & Expt Epilepsy, London, England
[2] Inst Neurol, Dept Neuroimmunol Neuroinflammat & Multiple Scler, NMR Res Unit, London WC1N 3BG, England
[3] UCL, Natl Hosp Neurol & Neurosurg, London, England
基金
英国医学研究理事会;
关键词
D O I
10.1016/S0140-6736(02)08615-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diffusion tensor Imaging Is an Imaging method that Is sensitive to the molecular movement of water, which Indicates cellular Integrity and pathology. A patient with refractory epilepsy and normal conventional MRI was examined with diffusion tensor Imaging. An area of abnormal diffusion In the right frontal lobe was Identified and surgically resected. The patient had a good clinical outcome. Histopathological examination of the resected tissue showed gliosis. Our findings may affect the Investigation of similar patients, and provide histopathological confirmation of diffusion abnormalities.
引用
收藏
页码:1748 / 1751
页数:4
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