Worsening of multifocal motor neuropathy during pregnancy

被引:12
作者
Chaudhry, V
Escolar, DM
Cornblath, DR
机构
[1] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD USA
[2] Childrens Natl Med Ctr, Dept Neurol, Washington, DC 20010 USA
关键词
D O I
10.1212/WNL.59.1.139
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Three women with multifocal motor neuropathy (MMN) were treated during pregnancy. Compared with their pregestation strength, the women became weaker in previously involved muscles and showed new weakness in previously unaffected muscles. All were treated with IV immunogloblin all during pregnancy and improved in strength. After pregnancy, strength that in all patients returned to the prepregnancy state. The authors conclude pregnancy may worsen MMN.
引用
收藏
页码:139 / 141
页数:3
相关论文
共 10 条
[1]   Course and treatment of myasthenia gravis during pregnancy [J].
Batocchi, AP ;
Majolini, L ;
Evoli, A ;
Lino, MM ;
Minisci, C ;
Tonali, P .
NEUROLOGY, 1999, 52 (03) :447-452
[2]   Rate of pregnancy-related relapse in multiple sclerosis [J].
Confavreux, C ;
Hutchinson, M ;
Hours, MM ;
Cortinovis-Tourniaire, P ;
Moreau, T .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (05) :285-291
[3]   PURE MOTOR DEMYELINATING NEUROPATHY - DETERIORATION AFTER STEROID TREATMENT AND IMPROVEMENT WITH INTRAVENOUS IMMUNOGLOBULIN [J].
DONAGHY, M ;
MILLS, KR ;
BONIFACE, SJ ;
SIMMONS, J ;
WRIGHT, I ;
GREGSON, N ;
JACOBS, J .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1994, 57 (07) :778-783
[4]   IL-12, TNF-α, and hormonal changes during late pregnancy and early postpartum:: Implications for autoimmune disease activity during these times [J].
Elenkov, IJ ;
Wilder, RL ;
Bakalov, VK ;
Link, AA ;
Dimitrov, MA ;
Fisher, S ;
Crane, M ;
Kanik, KS ;
Chrousos, GP .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (10) :4933-4938
[6]   Hormonal alterations in rheumatoid arthritis, including the effects of pregnancy [J].
Kanik, KS ;
Wilder, RL .
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 2000, 26 (04) :805-+
[7]   Pregnancy in systemic lupus erythematosus [J].
Mok, CC ;
Wong, RWS .
POSTGRADUATE MEDICAL JOURNAL, 2001, 77 (905) :157-165
[8]   Multifocal motor neuropathy [J].
Nobile-Orazio, E .
JOURNAL OF NEUROIMMUNOLOGY, 2001, 115 (1-2) :4-18
[9]   Cytokine patterns in maternal blood after premature rupture of membranes [J].
Raghupathy, R ;
Makhseed, M ;
El-Shazly, S ;
Azizieh, F ;
Farhat, R ;
Ashkanani, L .
OBSTETRICS AND GYNECOLOGY, 2001, 98 (01) :122-126
[10]   Early pregnancy factor suppresses experimental autoimmune encephalomyelitis induced in Lewis rats with myelin basic protein and in SJL/J mice with myelin proteolipid protein peptide 139-151 [J].
Zhang, B ;
Harness, J ;
Somodevilla-Torres, MJ ;
Hillyard, NC ;
Mould, AW ;
Alewood, D ;
Love, SG ;
Alewood, PF ;
Greer, JM ;
Cavanagh, AC ;
McCombe, PA ;
Morton, H .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2000, 182 (01) :5-15