Synthesis of polyfluorodibenz[b,f][1,4]oxazepines by the cyclization of 2-[(polyfluorobenzylidene)amino]phenols

被引：31

作者：

Allaway, CL ^{[1
]}

Daly, M ^{[1
]}

Nieuwenhuyzen, M ^{[1
]}

Saunders, GC ^{[1
]}

机构：

[1] Queens Univ Belfast, Sch Chem, Belfast BT9 5AG, Antrim, North Ireland

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2002年 / 115卷 / 01期

关键词：

dibenzoxazepine; cyclisation; SNAr; crystal structure;

D O I：

10.1016/S0022-1139(02)00033-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Thermolysis of 2-[(polyfluorobenzylidene)amino]phenols in ethanol in the presence of triethylamine affords the corresponding fluorinated dibenz[b,f][1,4]oxazepines in moderate to high yields. The structures of 2- [(2,3,4,5,6-pentafluorobenzylidene)amino]phenol and 1,2,3,4- tetrafluorodibenzo[b,f][1,4]oxazepine have been determined by single-crystal X-ray diffraction. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：91 / 99

页数：9

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