Axin and hepatocellular carcinomas

被引：48

作者：

Clevers, H ^{[1
]}

机构：

[1] Univ Utrecht Hosp, Dept Immunol, Utrecht, Netherlands

[2] Ctr Biomed Genet, Utrecht, Netherlands

来源：

NATURE GENETICS | 2000年 / 24卷 / 03期

关键词：

D O I：

10.1038/73396

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A gene (AXIN1) encoding another component of the Wnt-signalling pathway is reported to be mutated in human tumours, underscoring the oncogenic consequences of inappropriate activation of developmental signalling pathways later in life. Inhibitors of these signals therefore represent potential agents with which to treat cancer.

引用

收藏

页码：206 / 208

页数：3

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