A p75NTR Pivoting Paradigm Propels Perspicacity

被引:7
作者
Barker, Philip A. [1 ]
机构
[1] McGill Univ, Montreal Neurol Inst, Ctr Neuronal Survival, Montreal, PQ H3A 2B4, Canada
关键词
NEUROTROPHIN RECEPTOR; DOMAIN;
D O I
10.1016/j.neuron.2009.04.005
中图分类号
Q189 [神经科学];
学科分类号
071006 [神经生物学];
摘要
The p75 neurotrophin receptor (p75(NTR)) is involved in numerous neuronal signaling paths but its fundamental signaling mechanisms are unknown. In this issue of Neuron, Vilar et al. show that p75NTR functions as a covalently crosslinked dinner to transduce NGF-induced signaling events.
引用
收藏
页码:3 / 5
页数:3
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