Predictors of outcome after temporal lobectomy for the treatment of intractable epilepsy

被引：200

作者：

Jeha, L. E.

Najm, I. M.

Bingaman, W. E.

Khandwala, F.

Widdess-Walsh, P.

Morris, H. H.

Dinner, D. S.

Nair, D.

Foldvary-Schaeffer, N.

Prayson, R. A.

Comair, Y.

O'Brien, R.

Bulacio, J.

Gupta, A.

Luders, H. O.

机构：

[1] Cleveland Clin Fdn, Dept Neurol, Cleveland, OH 44195 USA

[2] Cleveland Clin Fdn, Dept Neurosurg, Cleveland, OH 44195 USA

[3] Cleveland Clin Fdn, Dept Biostat, Cleveland, OH USA

[4] Cleveland Clin Fdn, Dept Pathol, Cleveland, OH 44195 USA

[5] Amer Univ Beirut, Dept Neurosurg, Beirut, Lebanon

[6] Hosp Ninos Santisima Trinidad, Dept Neurol, Cordoba, Argentina

[7] Pk Ridge Hosp, Asheville, NC USA

来源：

NEUROLOGY | 2006年 / 66卷 / 12期

关键词：

D O I：

10.1212/01.wnl.0000219810.71010.9b

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To assess short- and long-term seizure freedom, the authors reviewed 371 patients who underwent anterior temporal lobectomy to treat pharmacoresistant epilepsy. The mean follow-up duration was 5.5 years (range 1 to 14.1 years). Fifty-three percent of patients were seizure free at 10 years. The authors identified multiple predictors of recurrence. Results of EEG performed 6 months postoperatively correlated with occurrence and severity of seizure recurrence, in addition to breakthrough seizures with discontinuation of antiepileptic drugs.

引用

收藏

页码：1938 / 1940

页数：3

相关论文

共 10 条

[1] PREOPERATIVE MRI PREDICTS OUTCOME OF TEMPORAL LOBECTOMY - AN ACTUARIAL ANALYSIS [J].

BERKOVIC, SF ;

MCINTOSH, AM ;

KALNINS, RM ;

JACKSON, GD ;

FABINYI, GCA ;

BRAZENOR, GA ;

BLADIN, PF ;

HOPPER, JL .

NEUROLOGY, 1995, 45 (07) :1358-1363

[2] THE DECOMPOSITION OF TIME-VARYING HAZARD INTO PHASES, EACH INCORPORATING A SEPARATE STREAM OF CONCOMITANT INFORMATION [J].

BLACKSTONE, EH ;

NAFTEL, DC ;

TURNER, ME .

JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 1986, 81 (395) :615-624

[3] Seizure outcome after temporal lobectomy for temporal lobe epilepsy - A Kaplan-Meier survival analysis [J].

Foldvary, N ;

Nashold, B ;

Mascha, E ;

Thompson, EA ;

Lee, N ;

McNamara, JO ;

Lewis, DV ;

Luther, JS ;

Friedman, AH ;

Radtke, RA .

NEUROLOGY, 2000, 54 (03) :630-634

[4] Prognostic factors in the surgical treatment of medically intractable epilepsy associated with mesial temporal sclerosis [J].

Hennessy, MJ ;

Elwes, RDC ;

Rabe-Hesketh, S ;

Binnie, CD ;

Polkey, CE .

ACTA NEUROLOGICA SCANDINAVICA, 2001, 103 (06) :344-350

[5] Temporal lobe developmental malformations and hippocampal sclerosis - Epilepsy surgical outcome [J].

Kuzniecky, R ;

Ho, SS ;

Martin, R ;

Faught, E ;

Morawetz, R ;

Palmer, C ;

Gilliam, F .

NEUROLOGY, 1999, 52 (03) :479-484

[6] Temporal lobectomy: long-term seizure outcome, late recurrence and risks for seizure recurrence [J].

McIntosh, AM ;

Kalnins, RM ;

Mitchell, LA ;

Fabinyi, GCA ;

Briellmann, RS ;

Berkovic, SF .

BRAIN, 2004, 127 :2018-2030

[7] Seizure recurrence after planned discontinuation of antiepileptic drugs in seizure-free patients after epilepsy surgery:: A review of current clinical experience [J].

Schmidt, D ;

Baumgartner, T ;

Löscher, L .

EPILEPSIA, 2004, 45 (02) :179-186

[8] Seizure outcome after anterior temporal lobectomy and its predictors in patients with apparent temporal lobe epilepsy and normal MRI [J].

Sylaja, PN ;

Radhakrishnan, K ;

Kesavadas, C ;

Sarma, PS .

EPILEPSIA, 2004, 45 (07) :803-808

[9] FDG-positron emission tomography and invasive EEG, seizure focus detection and surgical outcome [J].

Theodore, WH ;

Sato, S ;

Kufta, CV ;

Gaillard, WD ;

Kelley, K .

EPILEPSIA, 1997, 38 (01) :81-86

[10] Long-term seizure outcome in patients initially seizure-free after resective epilepsy surgery [J].

Yoon, HH ;

Kwon, HL ;

Mattson, RH ;

Spencer, DD ;

Spencer, SS .

NEUROLOGY, 2003, 61 (04) :445-450