No evidence for an association of ocular adnexal lymphoma with Chlamydia psittaci in a cohort of patients from the Netherlands

被引：56

作者：

Mulder, Marijn M. S.

Heddema, Edou R.

Pannekoek, Yvonne

Fairidpooya, Koorosh

Oud, Monique E. C. M.

Schilder-Tol, Esther

Saeed, Peerooz

Pals, Steven T.

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Pathol, NL-1105 AZ Amsterdam, Netherlands

[2] Univ Amsterdam, Acad Med Ctr, Dept Med Microbiol, NL-1105 AZ Amsterdam, Netherlands

[3] Univ Amsterdam, Acad Med Ctr, Dept Ophthalmol, NL-1105 AZ Amsterdam, Netherlands

来源：

LEUKEMIA RESEARCH | 2006年 / 30卷 / 10期

关键词：

lymphoma; ocular; orbit; marginal zone; chlamydia;

D O I：

10.1016/j.leukres.2005.12.003

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Extra-nodal marginal zone B cell lymphomas (MZBCLs) of the mucosa-associated lymphoid tissues (MALT) arise at sites of chronic antigenic stimulation due to organ-specific autoimmunity or infections, like Helicobacter pylori-associated chronic gastritis and Borrelia burgdorferi dermatitis. Recently, conflicting data have been published regarding a possible association between Chlamydia psittaci and ocular adnexal MZBCL. In the present study, we analyzed a cohort of ocular adnexal MZBLs from the Netherlands for the presence of C. psittaci DNA. We found no evidence for the presence of C. psittaci DNA in any of the tumor samples studied. Our data do no support a role for C. psittaci in the pathogenesis of ocular adnexal lymphomas in patients from the Netherlands. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1305 / 1307

页数：3

共 13 条

[1]

Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity [J].