Combined quinacrine and chlorpromazine therapy in fatal familial insomnia

被引：35

作者：

Benito-León, J ^{[1
]}

机构：

[1] Mostoles Gen Hosp, Serv Neurol, Madrid, Spain

来源：

CLINICAL NEUROPHARMACOLOGY | 2004年 / 27卷 / 04期

关键词：

prion disease; fatal familial insomnia; quinacrine; chlorpromazine; treatment;

D O I：

10.1097/01.wnf.0000134853.36429.0e

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Prion diseases are invariably fatal. Recently, quinacrine and chlorpromazine have been suggested as immediate candidates for the treatment of Creutzfeldt-Jakob disease and other prion diseases. The objective of this paper was to report on 2 fatal familial insomnia patients whose overall condition worsened despite quinacrine and chlorpromazine treatment.

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收藏

页码：201 / 203

页数：3

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