Molecular mechanisms of liver development and differentiation

被引：73

作者：

Darlington, GJ

机构：

[1] Baylor Coll Med, Huffington Ctr Aging, Houston, TX 77030 USA

[2] Baylor Coll Med, Dept Pathol, Houston, TX 77030 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1999年 / 11卷 / 06期

关键词：

D O I：

10.1016/S0955-0674(99)00035-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent advances in identifying molecular signals that dictate liver development and differentiation have come from analysis of several experimental systems including the developing embryo, cell and tissue culture, knockout mice and transplantation of hepatic precursor cells. Fibroblast growth factors and several families of transcription factors including hepatocyte nuclear factors 1, 3 and 4 and CCAAT/enhancer-binding protein have been shown to be important components of the differentiation process that culminates in the fully functional liver.

引用

页码：678 / 682

页数：5

共 32 条

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