New disguises for an old channel:: MaxiK channel β-subunits

被引：269

作者：

Orio, P ^{[1
]}

Rojas, P

Ferreira, G

Latorre, R

机构：

[1] Ctr Estudios Cient, Valdivia, Chile

[2] Univ Chile, Fac Ciencias, Dept Biol, Santiago, Chile

[3] Univ Calif Los Angeles, Sch Med, Dept Physiol & Anesthesiol, Los Angeles, CA 90095 USA

[4] Univ Republica, Dept Biofis, Fac Med, Montevideo, Uruguay

来源：

NEWS IN PHYSIOLOGICAL SCIENCES | 2002年 / 17卷

关键词：

D O I：

10.1152/nips.01387.2002

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Ca2+-activated K+ channels of large conductance (MaxiK or BK channels) control a large variety of physiological processes, including smooth muscle tone, neurosecretion, and hearing. Despite being coded by a single gene (Slowpoke), the diversity of MaxiK channels is great. Regulatory beta-subunits, splicing, and metabolic regulation create this diversity fundamental to the adequate function of many tissues.

引用

收藏

页码：156 / 161

页数：6

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