Phosphatases and kinases delivered to the host cell by bacterial pathogens

被引：89

作者：

DeVinney, R ^{[1
]}

Steele-Mortimer, O ^{[1
]}

Finlay, BB ^{[1
]}

机构：

[1] Univ British Columbia, Biotechnol Lab, Vancouver, BC V6T 1Z3, Canada

来源：

TRENDS IN MICROBIOLOGY | 2000年 / 8卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S0966-842X(99)01657-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Gram-negative type III secretion pathway translocates bacterial proteins directly into eukaryotic host cells, thus allowing a pathogen to interfere directly with host signalling pathways. Protein and inositol phosphatases and protein kinases have been identified as delivered effecters in three bacterial pathogens, Salmonella, Shigella and Yersinia, and it is expected that several more such type III effecters will be found.

引用

页码：29 / 33

页数：5

共 26 条

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