Persistent asthma: disease control, resource utilisation and direct costs

被引:97
作者
Van Ganse, E
Laforest, L
Pietri, G
Boissel, JP
Gormand, F
Ben-Joseph, R
Ernst, P
机构
[1] Hop Edouard Herriot, Ctr Antipoison, Ctr Pharmacovigilance, F-69347 Lyon 03, France
[2] Univ Lyon 1, Pharmacoepidemiol Unit, EA643, F-69365 Lyon, France
[3] Univ Lyon 1, Poison Ctr, F-69365 Lyon, France
[4] Univ Lyon 1, Clin Pharmacol Unit, EA643, F-69365 Lyon, France
[5] S Lyon Hosp Ctr Univ Hosp, Lyon, France
[6] Merck & Co Inc, Whitehouse Stn, NJ USA
[7] McGill Univ, Pharmacoepidemiol Unit, Montreal, PQ, Canada
关键词
asthma; control; health economics; resource utilisation; severity; therapy;
D O I
10.1183/09031936.02.02542001
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Despite evidence that adverse outcomes are less frequent when asthma management is optimised, the link bet wen the level of control, disease severity and medical resource utilisation (MRU) is poorly documented. This relationship was investigated in a group of patients suffering from persistent asthma (Global Initiative for Asthma (GINA) greater than or equal to2) in France. In 1998 a computerised family practice database was used to identify asthma patients aged 17-50 yrs. Information from the database was complemented by a patient survey to retrospectively assess the level of asthma control and hospital contacts. Costs of MRU over a 12-month study period were related to demographics, medical history asthma control, and doses of inhaled corticosteroids prescribed during the prestudy period. A review of the computerised medical database identified 1,038 adult patients with persistent asthma, who completed the survey questionnaire. Over a 12-month period, the mean cost of MRU was 549.8 is an element of for well-controlled patients, 746.3 is an element of per patient with moderate control, and 1,451.3 is an element of per patient with poor control. Costs also increased significantly with age, access to free asthma care, comorbid conditions, asthma symptoms in the past year and whether inhaled corticosteroids had been prescribed before the study period. In patients with persistent asthma, large differences were observed in the use of medical resources according to control and severity. Therefore, if patients appropriately use prescribed control therapy, their use of medical resources may be reduced.
引用
收藏
页码:260 / 267
页数:8
相关论文
共 26 条
[1]   Patient preferences for autonomy in decision making in asthma management [J].
Adams, RJ ;
Smith, BJ ;
Ruffin, RE .
THORAX, 2001, 56 (02) :126-132
[2]   The costs of asthma [J].
Barnes, PJ ;
Jonsson, B ;
Klim, JB .
EUROPEAN RESPIRATORY JOURNAL, 1996, 9 (04) :636-642
[3]   Under-treatment in a nonselected population of adult patients with asthma [J].
Bousquet, J ;
Knani, J ;
Henry, C ;
Liard, R ;
Richard, A ;
Michel, FB ;
Neukirch, F .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1996, 98 (03) :514-521
[4]   Asthma control versus asthma severity [J].
Cockcroft, DW ;
Swystun, VA .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1996, 98 (06) :1016-1018
[5]   Monitoring the patient with asthma: An evidence-based approach [J].
Gibson, PG .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2000, 106 (01) :17-26
[6]  
*GLOB IN ASTHM, 1995, NIH PUBL
[7]  
Godard P, 1998, EUR RESPIR J, V11, p2S
[8]   Factors associated with emergency department dependence of patients with asthma [J].
Hanania, NA ;
DavidWang, A ;
Kesten, S ;
Chapman, KR .
CHEST, 1997, 111 (02) :290-295
[9]  
Joseph KS, 1996, BMJ-BRIT MED J, V312, P79
[10]  
Krahn MD, 1996, CAN MED ASSOC J, V154, P821