Alcohol intake and risk of adenocarcinoma of the lung -: A case-control study in Uruguay

被引:19
作者
De Stefani, E [1 ]
Correa, P
Deneo-Pellegrini, H
Boffetta, P
Gutiérrez, LP
Ronco, A
Brennan, P
Mendilaharsu, M
机构
[1] Registro Nacl Canc, Montevideo, Uruguay
[2] Louisiana State Med Ctr, New Orleans, LA USA
[3] Int Agcy Res Canc, Unit Environm Canc Epidemiol, F-69372 Lyon, France
[4] Fac Med, Inst Neumol, Montevideo, Uruguay
关键词
alcohol; adenocarcinoma; lung cancer;
D O I
10.1016/S0169-5002(02)00153-8
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In order to examine in detail the relationship between alcohol drinking and risk of adenocarcinoma of the lung, a case-control study involving 160 cases of this cell type and 520 hospitalized controls was conducted in Uruguay in the time period January 1998-July 2000. Total alcohol intake was not associated with risk of adenocarcinoma of the lung (OR 1.2, 95% Cl 0.6-2.1). Also beer drinking was not associated with risk of carcinoma (OR 0.6, 95% CI 0.3-1.6). On the other hand, wine drinking displayed a marginally significant reduction in risk (OR 0.4, 95% Cl 0.2-1.1). On the contrary, hard liquor intake was associated with a 40% increase in risk of adenocarcinoma of the lung. These findings suggest that wine drinking has a protective effect in adenocarcinoma of the lung, whereas hard liquor increases moderately the risk of this cell type of lung cancer. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:9 / 14
页数:6
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