Clinical, microbiological, and economic benefit of a change in antibiotic prophylaxis for cardiac surgery

被引：36

作者：

Spelman, D ^{[1
]}

Harrington, G ^{[1
]}

Russo, P ^{[1
]}

Wesselingh, S ^{[1
]}

机构：

[1] Alfred Hosp, Infect Control & Hosp Epidemiol Unit, Prahran, Vic 3181, Australia

来源：

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY | 2002年 / 23卷 / 07期

关键词：

D O I：

10.1086/502074

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Vancomycin and rifampicin replaced cephazolin as antibiotic prophylaxis for coronary artery bypass surgery at our institution. Following this intervention, there was a significant decrease (P < .001) in the surgical-site infection rate from 10.5 (95% confidence interval, 8.2 to 13.3) to 4.9 (95% confidence interval, 3.2 to 7.1) infections per 100 procedures. An estimated $576,655 (Australian) was saved between two 12-month periods.

引用

页码：402 / 404

页数：3

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