Increased aquaporin I water channel expression in human brain tumours

被引：234

作者：

Saadoun, S

Papadopoulos, MC

Davies, DC

Bell, BA

Krishna, S

机构：

[1] Atkinson Morleys Hosp, Dept Neurosurg, London SW20 0NE, England

[2] St George Hosp, Sch Med, Dept Infect Dis, London SW17 0RE, England

[3] St George Hosp, Sch Med, Dept Anat & Dev Biol, London SW17 0RE, England

来源：

BRITISH JOURNAL OF CANCER | 2002年 / 87卷 / 06期

关键词：

adenocarcinoma; brain neoplasms; brain oedema; cytotoxic oedema; glioma; vasogenic oedema;

D O I：

10.1038/sj.bjc.6600512

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Aquaporin I is a water channel protein. There was little aquaporin I immunoreactivity in normal brain parenchyma. In astrocytomas, aquaporin I was expressed in microvessel endothelia and neoplastic astrocytes. In metastatic carcinomas, aquaporin I was present in microvessel endothelia and reactive astrocytes. Aquaporin I may participate in the formation of brain tumour oedema. (C) 2002 Cancer Research UK.

引用

页码：621 / 623

页数：3

共 6 条

[1] Water channel (aquaporin 1) expression and distribution in mammary carcinomas and glioblastomas [J].