High-throughput protein expression for the post-genomic era

被引:24
作者
Chambers, SP [1 ]
机构
[1] Vertex Pharmaceut, Cambridge, MA 02139 USA
关键词
D O I
10.1016/S1359-6446(02)02361-9
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
In the past, protein expression has been perceived as the principle bottleneck in protein characterization and structure determination. The challenge now is to rapidly express large numbers of genes in the search for new drug targets and therapeutic proteins encoded by the human genome. In this competitive environment, several high-throughput expression strategies for protein production are being used to industrialize the process of protein expression.
引用
收藏
页码:759 / 765
页数:7
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