A new cytotoxic 2-(2-phenylethyl)chromone from Chinese eaglewood

被引：73

作者：

Liu, Jun ^{[1
]}

Wu, Jiao ^{[1
]}

Zhao, You Xing ^{[2
]}

Deng, Yuan Yuan ^{[1
]}

Mei, Wen Li ^{[1
]}

Dai, Hao Fu ^{[1
]}

机构：

[1] Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China

[2] Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2008年 / 19卷 / 08期

关键词：

Chinese eaglewood; Aquilaria sinensis; Chromone; Cytotoxicity;

D O I：

10.1016/j.cclet.2008.05.034

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new compound 8-chloro-5,6,7-trihydroxy-2-(3-hydroxy-4-methoxyphenethyl)-5,6,7,8-tetrahydro-4H-chromen-4-one (1) was isolated from the Chinese eaglewood [Aquilaria sinensis (Lour.) Gilg]. Its structure was elucidated on the basis of spectral data. Compound 1 showed cytotoxicity against human gastric cancer cell line (SGC-7901) in vitro by MTT method with the IC50 value of 14.6 mu g/mL. (C) 2008 Wen Li Mei. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

引用

页码：934 / 936

页数：3