Lithiated benzyllithiums from chlorobenzyl chlorides by a DTBB-catalysed lithiation

被引：17

作者：

Gomez, C ^{[1
]}

Huerta, FF ^{[1
]}

Yus, M ^{[1
]}

机构：

[1] UNIV ALICANTE,FAC CIENCIAS,DEPT QUIM ORGAN,E-03080 ALICANTE,SPAIN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 04期

关键词：

D O I：

10.1016/S0040-4039(96)02393-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of 2-, 3- or 4-chlorobenzyl chlorides (1a-c) with an excess of lithium and a catalytic amount of DTBB (7 mol%) in the presence of different electrophiles [(PrCHO)-C-i, Bu(t)CHO, Et(2)CO(1) (CH2)(5)CO, PhCOMe, Me(3)SiCl] in THF at -50 degrees C leads after hydrolysis with water, to the expected dioles or disilylated compounds 2aa-2cf. (C) 1997, Elsevier Science Ltd.

引用

页码：687 / 690

页数：4

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