Ca2+-dependent regulation in neuronal gene expression

被引：264

作者：

Bito, H ^{[1
]}

Deisseroth, K ^{[1
]}

Tsien, RW ^{[1
]}

机构：

[1] KYOTO UNIV,FAC MED,DEPT PHARMACOL,SAKYO KU,KYOTO 60601,JAPAN

来源：

CURRENT OPINION IN NEUROBIOLOGY | 1997年 / 7卷 / 03期

关键词：

D O I：

10.1016/S0959-4388(97)80072-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

Ca2+ is an important signal-transduction molecule that plays a role in many intracellular signaling pathways. Recent advances have indicated that in neurons, Ca2+-controlled signaling mechanisms cooperate in order to discriminate amongst incoming cellular inputs. Ca2+-dependent transcriptional events can thereby be made selectively responsive to bursts of synaptic activity of specific intensity or duration.

引用

页码：419 / 429

页数：11

共 139 条

[1]

Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory [J].

Abel, T ;

Nguyen, PV ;

Barad, M ;

Deuel, TAS ;

Kandel, ER .

CELL, 1997, 88 (05) :615-626

[2]

IMMEDIATE-EARLY GENE-EXPRESSION ASSOCIATED WITH THE PERSISTENCE OF HETEROSYNAPTIC LONG-TERM DEPRESSION IN THE HIPPOCAMPUS [J].

ABRAHAM, WC ;

CHRISTIE, BR ;

LOGAN, B ;

LAWLOR, P ;

DRAGUNOW, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (21) :10049-10053

[3]

A MOLECULAR SWITCH FOR THE CONSOLIDATION OF LONG-TERM-MEMORY - CAMP-INDUCIBLE GENE-EXPRESSION [J].

ALBERINI, CM ;

GHIRARDI, M ;

HUANG, YY ;

NGUYEN, PV ;

KANDEL, ER .

DNA: THE DOUBLE HELIX: PERSPECTIVE AND PROSPECTIVE AT FORTY YEARS, 1995, 758 :261-286

[4]

Activation of a calcium-calmodulin-dependent protein kinase I cascade in PC12 cells [J].

Aletta, JM ;

Selbert, MA ;

Nairn, AC ;

Edelman, AM .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (34) :20930-20934

[5]

INDUCTION OF BETA-A ACTIVIN EXPRESSION BY SYNAPTIC ACTIVITY AND DURING NEOCORTICAL DEVELOPMENT [J].

ANDREASSON, K ;

WORLEY, PF .

NEUROSCIENCE, 1995, 69 (03) :781-796

[6]

An essential role for p300/CBP in the cellular response to hypoxia [J].

Arany, Z ;

Huang, LE ;

Eckner, R ;

Bhattacharya, S ;

Jiang, C ;

Goldberg, MA ;

Bunn, HF ;

Livingston, DM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (23) :12969-12973

[7]

REGULATION OF GENE-EXPRESSION IN HIPPOCAMPAL-NEURONS BY DISTINCT CALCIUM SIGNALING PATHWAYS [J].

BADING, H ;

GINTY, DD ;

GREENBERG, ME .

SCIENCE, 1993, 260 (5105) :181-186

[8]

Epidermal growth factor (EGF)-induced generation of hydrogen peroxide - Role in EGF receptor-mediated tyrosine phosphorylation [J].

Bae, YS ;

Kang, SW ;

Seo, MS ;

Baines, IC ;

Tekle, E ;

Chock, PB ;

Rhee, SG .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (01) :217-221

[9]

SEROTONIN-MEDIATED ENDOCYTOSIS OF APCAM - AN EARLY STEP OF LEARNING-RELATED SYNAPTIC GROWTH IN APLYSIA [J].

BAILEY, CH ;

CHEN, M ;

KELLER, F ;

KANDEL, ER .

SCIENCE, 1992, 256 (5057) :645-649

[10]

Toward a molecular definition of long-term memory storage [J].

Bailey, CH ;

Bartsch, D ;

Kandel, ER .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (24) :13445-13452

← 1 2 3 4 5 6 7 8 9 10 →