Misoprostol overdose during the first trimester of pregnancy

被引:8
作者
Bentov, Y [1 ]
Sheiner, E [1 ]
Katz, M [1 ]
机构
[1] Soroka Univ, Ctr Med, Dept Obstet & Gynecol, Beer Sheva, Israel
关键词
misoprostol; overdose; first trimester; pregnancy;
D O I
10.1016/j.ejogrb.2003.10.004
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Misoprostol is a synthetic prostaglandin E1 used during the first trimester of pregnancy as an adjacent to RU486 for medical termination of pregnancy. We present a case of a healthy 23-year-old woman who was admitted due to misoprostol overdose, used to induce an illegal abortion. Manifestations of toxicity included abdominal pain, vomiting, diarrhea and confusion. Treatment was supportive and included gastric lavage and administration of activated charcoal. Recovery was completed within a few hours, and the patient was scheduled for a dilatation and curettage the following day. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:108 / 109
页数:2
相关论文
共 5 条
[1]   The pharmacokinetics of the prostaglandin E1 analogue misoprostol in plasma and colostrum after postpartum oral administration [J].
Abdel-Aleem, H ;
Villar, J ;
Gülmezoglu, AM ;
Mostafa, SA ;
Youssef, AA ;
Shokry, M ;
Watzer, B .
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2003, 108 (01) :25-28
[2]  
ALFIREVIC Z, 2003, COCHRANE LIB
[3]   Controlled release of leukaemia inhibitory factor (LIF) to tissues [J].
Austin, L ;
Bower, JJ ;
Kurek, JB ;
Muldoon, CM .
GROWTH FACTORS, 1997, 15 (01) :61-68
[4]   OVERDOSAGE OF MISOPROSTOL IN PREGNANCY [J].
BOND, GR ;
ZEE, AV .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1994, 171 (02) :561-562
[5]   ACUTE MISOPROSTOL TOXICITY [J].
GRABER, DJ ;
MEIER, KH .
ANNALS OF EMERGENCY MEDICINE, 1991, 20 (05) :549-551