Functional and evolutionary analysis of a eukaryotic parasitic genome

被引:64
作者
Vivarèst, CP
Gouy, M
Thomarat, F
Méténier, G
机构
[1] Univ Clermont Ferrand, CNRS, UMR 6023, LBP, F-63117 Aubiere, France
[2] Univ Lyon 1, CNRS, UMR 5558, Lab Biometrie & Biol Evolut, F-69622 Villeurbanne, France
关键词
D O I
10.1016/S1369-5274(02)00356-9
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The DNA sequences of the 11 linear chromosomes of the similar to2.9 Mbp genome of Encephalitozoon cuniculi, an obligate intracellular parasite of mammals, include similar to2000 putative protein-coding genes. The compactness of this genome is associated with the length reduction of various genes. Essential functions are dependent on a minimal set of genes. Phylogenetic analysis supports the hypotheses that microsporidia are related to fungi and have retained a mitochondrion-derived organelle, the mitosome.
引用
收藏
页码:499 / 505
页数:7
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