Electroanalysis of dopamine at a gold electrode modified with N-acetylcysteine self-assembled monolayer

被引：96

作者：

Liu, T

Li, MX ^{[1
]}

Li, QY

机构：

[1] Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China

[2] Beijing Inst Pharmacol & Toxicol, Beijing 100850, Peoples R China

来源：

TALANTA | 2004年 / 63卷 / 04期

基金：

中国国家自然科学基金;

关键词：

N-acetylcysteine; dopamine; ascorbic acid; SAM; modified electrode;

D O I：

10.1016/j.talanta.2004.01.019

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Voltammetric behavior of dopamine (DA) on a gold electrode modified with the self-assembled monolayer (SAM) of N-acetylcysteine has been investigated, and one pair of well-defined redox peaks of dopamine is obtained at the SAM modified gold electrode. The oxidation peak current increases linearly with the concentration of dopamine in the range of 1.0 x 10(-6) to 2.0 x 10(-4) mol l(-1). The detection limit is 8.0 x 10(-7) mol l(-1). This method will be applicable to the determination of dopamine in injection of dopamine hydrochloride, and the good recovery of dopamine is obtained. Furthermore, The SAM modified gold electrode can resolve well the voltammetric responses of dopamine and ascorbic acid (AA), so it can also be applied to the determination of dopamine in the presence of ascorbic acid. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：1053 / 1059

页数：7

共 28 条

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