APRV -: a program for automated data processing, refinement and visualization

被引:31
作者
Kroemer, M [1 ]
Dreyer, MK [1 ]
Wendt, KU [1 ]
机构
[1] Aventis Pharma Deutschland GmbH, Struct Biol, D-65926 Frankfurt, Germany
来源
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY | 2004年 / 60卷
关键词
D O I
10.1107/S0907444904015215
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
APRV (Automatic Processing, Refinement and Visualization) is a new program that enables high-throughput batch processing of crystallographic data. The program combines processing of raw diffraction images, initial structure refinement and visual inspection of resulting electron density into a seamless one-step procedure, during which all relevant parameters are refined automatically. It is controlled by a user-friendly graphical interface, facilitating operation by non-experts.
引用
收藏
页码:1679 / 1682
页数:4
相关论文
共 14 条
[1]  
*ACC INC, 2002, CNX US GUID
[2]   PHENIX:: building new software for automated crystallographic structure determination [J].
Adams, PD ;
Grosse-Kunstleve, RW ;
Hung, LW ;
Ioerger, TR ;
McCoy, AJ ;
Moriarty, NW ;
Read, RJ ;
Sacchettini, JC ;
Sauter, NK ;
Terwilliger, TC .
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2002, 58 :1948-1954
[3]  
Brunger AT, 1998, ACTA CRYSTALLOGR D, V54, P905, DOI 10.1107/s0907444998003254
[4]   Automated crystallographic system for high-throughput protein structure determination [J].
Brunzelle, JS ;
Shafaee, P ;
Yang, XJ ;
Weigand, S ;
Ren, Z ;
Anderson, WF .
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 2003, 59 :1138-1144
[5]   Structure-based screening of low-affinity compounds [J].
Carr, R ;
Jhoti, H .
DRUG DISCOVERY TODAY, 2002, 7 (09) :522-527
[6]   Improved R-factors for diffraction data analysis in macromolecular crystallography [J].
Diederichs, K ;
Karplus, PA .
NATURE STRUCTURAL BIOLOGY, 1997, 4 (04) :269-275
[7]   Automated protein crystal structure determination using ELVES [J].
Holton, J ;
Alber, T .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (06) :1537-1542
[8]   USING KNOWN SUBSTRUCTURES IN PROTEIN MODEL-BUILDING AND CRYSTALLOGRAPHY [J].
JONES, TA ;
THIRUP, S .
EMBO JOURNAL, 1986, 5 (04) :819-822
[9]   IMPROVED METHODS FOR BUILDING PROTEIN MODELS IN ELECTRON-DENSITY MAPS AND THE LOCATION OF ERRORS IN THESE MODELS [J].
JONES, TA ;
ZOU, JY ;
COWAN, SW ;
KJELDGAARD, M .
ACTA CRYSTALLOGRAPHICA SECTION A, 1991, 47 :110-119
[10]   AUTOMATIC-INDEXING OF ROTATION DIFFRACTION PATTERNS [J].
KABSCH, W .
JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1988, 21 :67-71