Adapter proteins in lymphocyte antigen-receptor signaling

被引：89

作者：

Myung, PS

Boerthe, NJ

Koretzky, GA

机构：

[1] Univ Penn, Grad Program Immunol, Leonard & Madlyn Abramson Family Canc Res Inst, Philadelphia, PA 19104 USA

[2] Univ Penn, Dept Pathol & Lab Med, Leonard & Madlyn Abramson Family Canc Res Inst, Philadelphia, PA 19104 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2000年 / 12卷 / 03期

关键词：

D O I：

10.1016/S0952-7915(00)00085-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Adapter molecules contain discrete modular domains that direct specific intermolecular interactions to orchestrate assembly of signaling complexes. A number of adapter proteins play critical roles in both positive and negative regulation of antigen-receptor signaling, influencing lymphocyte development and function.

引用

收藏

页码：256 / 266

页数：11

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