Hyphal forms in the central nervous system of patients with coccidioidomycosis

被引：19

作者：

Hagman, HM

Madnick, EG

D'Agostino, AN

Williams, PL

Shatsky, S

Mirels, LF

Tucker, RM

Rinaldi, MG

Stevens, DA

Bryant, RE

机构：

[1] Santa Clara Valley Med Ctr, Dept Med, San Jose, CA 95128 USA

[2] Santa Clara Valley Med Ctr, Dept Neurosurg, San Jose, CA 95128 USA

[3] Stanford Univ, San Jose, CA USA

[4] Mission Viejo Community Hosp, Dept Med, Mission Viejo, CA 92690 USA

[5] Kaweah Delta Hosp, Dept Med, Visalia, CA USA

[6] Oregon Hlth Sci Univ, Dept Med, Portland, OR 97201 USA

[7] Oregon Hlth Sci Univ, Dept Pathol, Portland, OR 97201 USA

[8] Univ Texas, Hlth Sci Ctr, Dept Microbiol, San Antonio, TX 78284 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2000年 / 30卷 / 02期

关键词：

D O I：

10.1086/313643

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Coccidioides immitis is a dimorphic fungus that grows as a filamentous mold in soil and as a spherule at human body temperature. The hyphal or soil form is found rarely in human tissue. We report 5 cases of coccidioidomycosis in which hyphae were found in brain tissue or spinal fluid, The presence of central nervous system plastic devices appears to be associated with morphological reversion to the saprophytic form. This reversion has implications for diagnosis and therapy and may increase the risk of obstruction of the device(s).

引用

页码：349 / 355

页数：7

共 22 条

[1]

AMPEL NM, 1989, REV INFECT DIS, V11, P897

[2] Central nervous system abscesses due to Coccidioides species [J].