Ultrafast decay and hydration dynamics of DNA bases and mimics

被引：56

作者：

Pal, SK ^{[1
]}

Peon, J ^{[1
]}

Zewail, AH ^{[1
]}

机构：

[1] CALTECH, Arthur Amos Noyes Lab Chem Phys, Lab Mol Sci, Pasadena, CA 91125 USA

来源：

CHEMICAL PHYSICS LETTERS | 2002年 / 363卷 / 1-2期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0009-2614(02)01149-1

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The ultrafast decay of the excited-state of DNA bases, reported here and elsewhere [Peon & Zewail, Chem. Phys. Lett. 348 (2001) 255], makes very difficult the probing of the full hydration dynamics in DNA. Here we present studies of the natural DNA base mimic, 2-aminopurine (2AP), whose excited-state decay is much longer, in water and, for comparison, in bulk ethanol. Guided by these solvation results, which directly reflect the role of orientational and translational diffusion, we reexamine the ultrafast decay rates for the natural nucleotides and nucleosides. The results are important for the mechanism of energy disposal in DNA. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：57 / 63

页数：7

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