Segregation of separate steps in chromium-catalyzed reactions for convenience and mechanistic analysis

被引：9

作者：

Hari, A ^{[1
]}

Miller, BL ^{[1
]}

机构：

[1] Univ Rochester, Dept Chem, Rochester, NY 14627 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 05期

关键词：

D O I：

10.1021/ol0055364

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] We have developed an apparatus for carrying out redox-coupled chromium-manganese or chromium-zinc reactions on solid-supported substrates which allows recycling of the stoichiometric reductant. In addition to providing a greatly simplified procedure for these reactions, we observe striking differences in the recyclability of Mn and Zn. A preliminary extension of the methodology to the catalytic coupling of allylchromium reagents with solid-supported aldehydes is also reported.

引用

页码：691 / 693

页数：3

共 18 条

[1] A variant of the Takai-Utimoto reaction of acrolein acetals with aldehydes catalytic in chromium: A highly stereoselective route to anti diol derivatives [J].