The relationship between restrictive and repetitive behaviors in individuals with autism and obsessive compulsive symptoms in parents

被引:30
作者
Abramson, R. K.
Ravan, S. A.
Wright, H. H.
Wieduwilt, K.
Wolpert, C. M.
Donnelly, S. A.
Pericak-Vance, M. A.
Cuccaro, M. L.
机构
[1] Duke Univ, Med Ctr, Ctr Human Genet, Durham, NC 27710 USA
[2] Univ S Carolina, WS Hall Psychiat Inst, Columbia, SC 29208 USA
关键词
autism; repetitive behaviors; insistence on sameness; obsessive-compulsive features; phenotype;
D O I
10.1007/s10578-005-2973-7
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
This study investigated the relationship between repetitive behaviors in individuals with autism and obsessive-compulsive behaviors in parents. We hypothesized that repetitive behaviors in probands with autism would be associated with increased obsessive-compulsive behaviors in parents in sporadic families (1 known case of autism per family and no known history of autism). Parents with clinically significant Y-BOCS scores were more likely to have a family history of obsessive-compulsive disorder. The empirically derived Autism Diagnostic Interview-R (ADI-R) factor, Insistence on Sameness, was positively correlated with obsessive-compulsive behaviors in parents. Further, when probands were grouped on the basis of parental Y-BOCS scores (clinically significant versus non-clinically significant), probands whose parents had clinically significant Y-BOCS scores had higher ADI-R Insistence on Sameness factor scores. The findings of the current study of sporadic families extend previous work that has shown an association between restrictive/repetitive behaviors in probands with autism and obsessive-compulsive features in parents.
引用
收藏
页码:155 / 165
页数:11
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