The ZIP family of metal transporters

被引:831
作者
Guerinot, ML [1 ]
机构
[1] Dartmouth Coll, Dept Biol Sci, Hanover, NH 03755 USA
来源
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 2000年 / 1465卷 / 1-2期
基金
美国国家科学基金会;
关键词
ZIP family; iron; zinc; manganese; cadmium;
D O I
10.1016/S0005-2736(00)00138-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Members of the ZIP gene family, a novel metal transporter family first identified in plants, are capable of transporting a variety of cations, including cadmium, iron, manganese and zinc. Information on where in the plant each of the ZIP transporters functions and how each is controlled in response to nutrient availability may allow the manipulation of plant mineral status with an eye to (1) creating food crops with enhanced mineral content, and (2) developing crops that bioaccumulate or exclude toxic metals. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:190 / 198
页数:9
相关论文
共 49 条
[1]   Evolution of substrate specificities in the P-type ATPase superfamily [J].
Axelsen, KB ;
Palmgren, MG .
JOURNAL OF MOLECULAR EVOLUTION, 1998, 46 (01) :84-101
[2]   The galvanization of biology: A growing appreciation for the roles of zinc [J].
Berg, JM ;
Shi, YG .
SCIENCE, 1996, 271 (5252) :1081-1085
[3]   Phytomining [J].
Brooks, RR ;
Chambers, MF ;
Nicks, LJ ;
Robinson, BH .
TRENDS IN PLANT SCIENCE, 1998, 3 (09) :359-362
[4]   NRAMP DEFINES A FAMILY OF MEMBRANE-PROTEINS [J].
CELLIER, M ;
PRIVE, G ;
BELOUCHI, A ;
KWAN, T ;
RODRIGUES, V ;
CHIA, W ;
GROS, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (22) :10089-10093
[5]   Zinc fingers in Caenorhabditis elegans:: Finding families and probing pathways [J].
Clarke, ND ;
Berg, JM .
SCIENCE, 1998, 282 (5396) :2018-2022
[6]   The role of iron-deficiency stress responses in stimulating heavy-metal transport in plants [J].
Cohen, CK ;
Fox, TC ;
Garvin, DF ;
Kochian, LV .
PLANT PHYSIOLOGY, 1998, 116 (03) :1063-1072
[7]  
COHEN CK, 1998, PLANT PHYSL
[8]   Evidence for a zinc uptake transporter in human prostate cancer cells which is regulated by prolactin and testosterone [J].
Costello, LC ;
Liu, YY ;
Zou, J ;
Franklin, RB .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (25) :17499-17504
[9]   Plants ectopically expressing the iron-binding protein, ferritin, are tolerant to oxidative damage and pathogens [J].
Deák, M ;
Horváth, GV ;
Davletova, S ;
Török, K ;
Sass, L ;
Vass, I ;
Barna, B ;
Király, Z ;
Dudits, D .
NATURE BIOTECHNOLOGY, 1999, 17 (02) :192-196
[10]  
DIX DR, 1994, J BIOL CHEM, V269, P26092