NIH to balance sex in cell and animal studies

被引：1288

作者：

Clayton, Janine A. ^{[1
]}

Collins, Francis S. ^{[2
]}

机构：

[1] US Natl Inst Hlth, Off Res Womens Hlth, Bethesda, MD 20892 USA

[2] US Natl Inst Hlth, Bethesda, MD USA

来源：

NATURE | 2014年 / 509卷 / 7500期

关键词：

EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; MULTIPLE-SCLEROSIS;

D O I：

10.1038/509282a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];

摘要：

Janine A. Clayton and Francis S. Collins unveil policies to ensure that preclinical research funded by the US National Institutes of Health considers females and males.

引用

页码：282 / 283

页数：2

共 15 条

[1]

Strategies and methods for research on sex differences in brain and behavior [J].

Becker, JB ;

Arnold, AP ;

Berkley, KJ ;

Blaustein, JD ;

Eckel, LA ;

Hampson, E ;

Herman, JP ;

Marts, S ;

Sadee, W ;

Steiner, M ;

Taylor, J ;

Young, E .

ENDOCRINOLOGY, 2005, 146 (04) :1650-1673

[2]

Sex bias in neuroscience and biomedical research [J].

Beery, Annaliese K. ;

Zucker, Irving .

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2011, 35 (03) :565-572

[3]

The Number of X Chromosomes Causes Sex Differences in Adiposity in Mice [J].

Chen, Xuqi ;

McClusky, Rebecca ;

Chen, Jenny ;

Beaven, Simon W. ;

Tontonoz, Peter ;

Arnold, Arthur P. ;

Reue, Karen .

PLOS GENETICS, 2012, 8 (05)

[4]

NIH plans to enhance reproducibility [J].

Collins, Francis S. ;

Tabak, Lawrence A. .

NATURE, 2014, 505 (7485) :612-613

[5]

Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway [J].

Du, LN ;

Bayir, H ;

Lai, YC ;

Zhang, XP ;

Kochanek, PM ;

Watkins, SC ;

Graham, SH ;

Clark, RSB .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (37) :38563-38570

[6]

XY sex chromosome complement, compared with XX, in the CNS confers greater neurodegeneration during experimental autoimmune encephalomyelitis [J].

Du, Sienmi ;

Itoh, Noriko ;

Askarinam, Sahar ;

Hill, Haley ;

Arnold, Arthur P. ;

Voskuhl, Rhonda R. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (07) :2806-2811

[7]

Parent-of-origin effect in multiple sclerosis: observations in half-siblings [J].

Ebers, GC ;

Sadovnick, AD ;

Dyment, DA ;

Yee, IML ;

Willer, CJ ;

Risch, N .

LANCET, 2004, 363 (9423) :1773-1774

[8]

Sex Differences in Guanfacine Effects on Drug Craving and Stress Arousal in Cocaine-Dependent Individuals [J].

Fox, Helen C. ;

Morgan, Peter T. ;

Sinha, Rajita .

NEUROPSYCHOPHARMACOLOGY, 2014, 39 (06) :1527-1537

[9]

Gender differences in drug responses [J].

Franconi, Flavia ;

Brunelleschi, Sandra ;

Steardo, Luca ;

Cuomo, Vincenzo .

PHARMACOLOGICAL RESEARCH, 2007, 55 (02) :81-95

[10]

A call for transparent reporting to optimize the predictive value of preclinical research [J].

Landis, Story C. ;

Amara, Susan G. ;

Asadullah, Khusru ;

Austin, Chris P. ;

Blumenstein, Robi ;

Bradley, Eileen W. ;

Crystal, Ronald G. ;

Darnell, Robert B. ;

Ferrante, Robert J. ;

Fillit, Howard ;

Finkelstein, Robert ;

Fisher, Marc ;

Gendelman, Howard E. ;

Golub, Robert M. ;

Goudreau, John L. ;

Gross, Robert A. ;

Gubitz, Amelie K. ;

Hesterlee, Sharon E. ;

Howells, David W. ;

Huguenard, John ;

Kelner, Katrina ;

Koroshetz, Walter ;

Krainc, Dimitri ;

Lazic, Stanley E. ;

Levine, Michael S. ;

Macleod, Malcolm R. ;

McCall, John M. ;

Moxley, Richard T., III ;

Narasimhan, Kalyani ;

Noble, Linda J. ;

Perrin, Steve ;

Porter, John D. ;

Steward, Oswald ;

Unger, Ellis ;

Utz, Ursula ;

Silberberg, Shai D. .

NATURE, 2012, 490 (7419) :187-191

← 1 2 →