Antibiotic susceptibility patterns of Helicobacter pylori strains isolated from northeastern Mexico

被引：13

作者：

Garza-González, E ^{[1
]}

Pérez-Pérez, GI ^{[1
]}

Alanís-Aguilar, O ^{[1
]}

Tijerina-Menchaca, R ^{[1
]}

Maldonado-Garza, HJ ^{[1
]}

Bosques-Padilla, FJ ^{[1
]}

机构：

[1] Univ Autonoma Nuevo Leon, Fac Med, Dept Microbiol, Monterrey, Mexico

来源：

JOURNAL OF CHEMOTHERAPY | 2002年 / 14卷 / 04期

关键词：

Helicobacter pylori; bacterial resistance; antimicrobial susceptibility; testing; metronidazole; clarithromycin;

D O I：

10.1179/joc.2002.14.4.342

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

There are reports of increased antibiotic resistance rates in Helicobacter pylori strains around the world. The aim of this study was to determine the susceptibility patterns in H. pylori strains isolated in Monterrey, Mexico. We studied 62 strains isolated from the same number of symptomatic adult patients. Metronidazole (Mtz), clarithromycin (Cla), amoxicillin (Amx) and tetracycline (Tet) were tested by the E-test method. We observed that 37.1% of the strains were resistant to Mtz (MIC greater than or equal to8 mg/L), and 8.1% to Cla (MIC greater than or equal to8 mg/L), but we did not observe resistance to Amx (MIC greater than or equal to2 mg/L) or Tet (MIC greater than or equal to4 mg/L). In northeastern Mexico, the percentage of resistant strains was similar to that observed in developed countries. These results confirm that it is necessary to evaluate the susceptibility patterns of H. pylori strains by geographic area.

引用

页码：342 / 345

页数：4

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