One-pot synthesis of dihydropyrimidinones using facile and reusable polyoxometalate catalysts for the Biginelli reaction

被引：87

作者：

Fazaeli, Razieh

Tangestaninejad, Shahram ^{[1
]}

Aliyan, Hamid

Moghadam, Majid

机构：

[1] Isfahan Univ, Dept Chem, Esfahan 8174673441, Iran

[2] Islamic Azad Univ, Shahreza Branch, Dept Chem, Tehran, Iran

[3] Univ Yasuj, Dept Chem, Yasuj 759147353, Iran

来源：

APPLIED CATALYSIS A-GENERAL | 2006年 / 309卷 / 01期

关键词：

Biginelli reaction; polyoxometalates (POMs); homogeneous; heterogeneous; multicomponent reactions (MCR); environmentally friendly processes;

D O I：

10.1016/j.apcata.2006.04.043

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The efficiency of various heteropoly compounds as well-known solid acids is investigated for the three-component condensation reaction of an aldehyde with beta-ketoester and urea in acetonitrile to afford the dihydropyrimidinones (DHPM). Compared to the classical Biginelli reaction conditions, this new method consistently has the advantage of excellent yields and short reaction times. Furthermore, the catalyst could be easily recovered after completion of the reaction and reused without a considerable change in its activity. (c) 2006 Elsevier B.V. All rights reserved.

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页码：44 / 51

页数：8

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