Cancer surveillance in ulcerative colitis: critical analysis of long-term prospective programme

被引:19
作者
Biasco, G
Rossini, FP
Hakim, R
Brandi, G
Di Battista, M
Di Febo, G
Calabrese, C
Santucci, R
Miglioli, M
机构
[1] Univ Bologna, Inst Haematol & Oncol L&A Seragnoli, I-40126 Bologna, Italy
[2] Univ Bologna, Interdipartimental Ctr Canc Res G Prodi, I-40126 Bologna, Italy
[3] S Giovanni Hosp, Gastroenterol Unit, Turin, Italy
关键词
colonoscopy; colorectal cancer; dysplasia; ulcerative colitis;
D O I
10.1016/S1590-8658(02)80127-X
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background. Patients with longstanding ulcerative colitis are at increased risk of colorectal cancer. In the literature, no agreement has yet been reached regarding prevention strategies. Our report sums up a prospective study started in 1980. Methods. A total of 65 patients affected by ulcerative colitis for more than seven years were admitted to a regular colonoscopic and biopsy follow-up programme. Results. Some 20 years after the beginning of the study, 23 (35.3%) patients have been operated upon, 2 patients have died but not from cancer, 29 (44.6%) patients have abandoned the programme. Only 11 (16.9%) patients have remained under colonoscopic surveillance. Conclusion. These results cast some doubts on the significance of such a programme and on its long-term feasibility.
引用
收藏
页码:339 / 342
页数:4
相关论文
共 30 条
[1]   Chronic ulcerative colitis associated with malignant disease [J].
Bargen, JA .
ARCHIVES OF SURGERY, 1928, 17 (04) :561-576
[2]  
BIASCO G, 1995, CANCER, V75, P2045, DOI 10.1002/1097-0142(19950415)75:8<2045::AID-CNCR2820750803>3.0.CO
[3]  
2-X
[4]  
Biasco G, 1997, Tumori, V83, pS5
[5]  
Biasco G, 1998, ITAL J GASTROENTEROL, V30, P426
[6]  
Biasco G, 1997, CANCER EPIDEM BIOMAR, V6, P469
[7]   CANCER SURVEILLANCE OF PATIENTS WITH LONGSTANDING ULCERATIVE-COLITIS - A CLINICAL, ENDOSCOPIC, AND HISTOLOGICAL STUDY [J].
BROSTROM, O ;
LOFBERG, R ;
OST, A ;
REICHARD, H .
GUT, 1986, 27 (12) :1408-1413
[8]   COLONOSCOPIC SURVEILLANCE REDUCES MORTALITY FROM COLORECTAL-CANCER IN ULCERATIVE-COLITIS [J].
CHOI, PM ;
NUGENT, FW ;
SCHOETZ, DJ ;
SILVERMAN, ML ;
HAGGITT, RC .
GASTROENTEROLOGY, 1993, 105 (02) :418-424
[9]   PARTICIPATION IN FECAL OCCULT BLOOD SCREENING FOR COLORECTAL-CANCER [J].
DENT, OF ;
BARTROP, R ;
GOULSTON, KJ ;
CHAPUIS, PH .
SOCIAL SCIENCE & MEDICINE, 1983, 17 (01) :17-23
[10]   CANCER RISK AND LIFE EXPECTANCY OF CHILDREN WITH ULCERATIVE COLITIS [J].
DEVROEDE, GJ ;
TAYLOR, WF ;
SAUER, WG ;
JACKMAN, RJ ;
STICKLER, GB .
NEW ENGLAND JOURNAL OF MEDICINE, 1971, 285 (01) :17-+