AbrB is a regulator of the δw regulon in Bacillus subtilis

被引：7

作者：

Qian, Q

Lee, CY

Helmann, JD

Strauch, MA

机构：

[1] Univ Maryland, Sch Dent, Dept Oral & Craniofacial Biol Sci, Baltimore, MD 21201 USA

[2] Cornell Univ, Microbiol Sect, Ithaca, NY 14853 USA

来源：

FEMS MICROBIOLOGY LETTERS | 2002年 / 211卷 / 02期

关键词：

Bacillus subtilis; antibiotics; AbrB; RNA polymerase; sporulation;

D O I：

10.1016/S0378-1097(02)00679-1

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The Bacillus subtilis global regulator AbrB was found to negatively control expression of sigW and genes of the sigma(W) regulon. AbrB bound to DNA regions in the autoregulatory sigW promoter and to some, but not all, of the other sigma(W)-dependent promoters in B. subtilis. Defects in antibiotic resistance properties caused by spo0A mutations are at least partially correlated with AbrB repression of the sigma(W) regulon, (C) 2002 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

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页码：219 / 223

页数：5

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