Genetic clues to the pathogenesis of Parkinson's disease

被引:196
作者
Vila, M [1 ]
Przedborski, S
机构
[1] Columbia Univ, Dept Neurol, New York, NY 10032 USA
[2] Columbia Univ, Dept Pathol, New York, NY 10032 USA
[3] Columbia Univ, Ctr Neurobiol & Behav, New York, NY 10032 USA
关键词
D O I
10.1038/nm1068
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent years have seen an explosion in the rate of discovery of genetic defects linked to Parkinson's disease. These breakthroughs have not provided a direct explanation for the disease process. Nevertheless, they have helped transform Parkinson's disease research by providing tangible clues to the neurobiology of the disorder.
引用
收藏
页码:S58 / S62
页数:5
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