Anterior-posterior polarity in C-elegans and Drosophila -: PARallels and differences

被引：104

作者：

Pellettieri, J ^{[1
]}

Seydoux, G ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Mol Biol & Genet, Baltimore, MD 21205 USA

来源：

SCIENCE | 2002年 / 298卷 / 5600期

关键词：

D O I：

10.1126/science.1072162

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The eggs of Caenorhabditis elegans and Drosophila bear little similarity to each other, yet both depend on the par genes for control of anterior-posterior polarity. Here we explore possible common roles for the par genes (pars) in converting transient asymmetries into stably polarized axes. Although clear mechanistic parallels remain to be established, par-dependent regulation of microtubule dynamics and protein stability emerge as common themes.

引用

页码：1946 / 1950

页数：5

共 55 条

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