Increased lovastatin formation by Aspergillus terreus using repeated fed-batch process

被引：60

作者：

Novak, N

Gerdin, S

Berovic, M

机构：

[1] National Institute of Chemistry, SI-1001 Ljubljana

来源：

BIOTECHNOLOGY LETTERS | 1997年 / 19卷 / 10期

关键词：

D O I：

10.1023/A:1018322628333

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Lovastatin biosynthesis with Aspergillus terreus in batch fermentation reached 160 U/l in 161 h at pH 6.8 and a dissolved O-2 tension maintained at 70%. At the end of repeated fed batch fermentations, the yield of lovastatin was increased by 37% though this took over twice as long as in the batch fermentation.

引用

页码：947 / 948

页数：2

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