Comparative in vitro activities of carbapenem L-749,345 and other antimicrobials against multiresistant gram-negative clinical pathogens

被引：43

作者：

Jacoby, G ^{[1
]}

Han, P ^{[1
]}

Tran, J ^{[1
]}

机构：

[1] EDITH NOURSE ROGERS MEM VET ADM HOSP,BEDFORD,MA 01730

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1997年 / 41卷 / 08期

关键词：

D O I：

10.1128/AAC.41.8.1830

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

Carbapenems L-749,345 and imipenem had the lowest MICs at which 90% of isolates were inhibited (0.5 mu g/ml) of 14 antimicrobial agents tested against 76 multiresistant gram-negative clinical isolates with TEM- or SHV-type extended-spectrum beta-lactamases and chromosomal or plasmid-determined AmpC beta-lactamases, but the MIC of L-749,345 for one isolate of Klebsiella pneumoniae was 16 mu g/ml.

引用

页码：1830 / 1831

页数：2

共 5 条

[1]

A FUNCTIONAL CLASSIFICATION SCHEME FOR BETA-LACTAMASES AND ITS CORRELATION WITH MOLECULAR-STRUCTURE [J].