ProTherm, version 2.0: thermodynamic database for proteins and mutants

被引：56

作者：

Gromiha, MM ^{[1
]}

An, JH ^{[1
]}

Kono, H ^{[1
]}

Oobatake, M ^{[1
]}

Uedaira, H ^{[1
]}

Prabakaran, P ^{[1
]}

Sarai, A ^{[1
]}

机构：

[1] Inst Phys & Chem Res, Tsukuba Life Sci Ctr, RIKEN, Tsukuba, Ibaraki 3050074, Japan

来源：

NUCLEIC ACIDS RESEARCH | 2000年 / 28卷 / 01期

关键词：

D O I：

10.1093/nar/28.1.283

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

ProTherm 2.0 is the second release of the Thermodynamic-Database for Proteins and Mutants that includes numerical data for several thermodynamic parameters, structural information, experimental methods and conditions, functional and literature information. The present release contains >5500 entries, an similar to 67% increase over the previous version. In addition, we have included information about reversibility of data, details about buffer and ion concentrations and the surrounding residues in space for all mutants. A WWW interface enables users to search data based on various conditions with different sorting options for outputs. Further, ProTherm has links with other structural and literature databases, and the mutation sites and:surrounding residues are automatically mapped on-the structures and can be directly viewed through 3DinSight developed in our laboratory. The ProTherm database is freely available through the WWW at http://www.rtc.riken.go.jp/protherm.html.

引用

页码：283 / 285

页数：3

共 9 条

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