Prevalence and associations of epiretinal membranes in Latinos: the Los Angeles Latino Eye Study

被引:106
作者
Fraser-Bell, S
Ying-Lai, M
Klein, R
Varma, R
机构
[1] Univ So Calif, Doheny Eye Inst, Los Angeles, CA 90089 USA
[2] Univ So Calif, Dept Ophthalmol, Keck Sch Med, Los Angeles, CA 90089 USA
[3] Univ Wisconsin, Dept Ophthalmol & Visual Sci, Madison, WI USA
[4] Univ So Calif, Dept Prevent Med, Los Angeles, CA 90089 USA
[5] Battelle Survey Res Ctr, St Louis, MO USA
[6] Univ Wisconsin, Ocular Epidemiol Grading Ctr, Madison, WI USA
关键词
D O I
10.1167/iovs.03-1295
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
PURPOSE. To determine age- and gender-specific prevalence and associations of epiretinal membranes (ERMs) in adult Latinos. METHODS. The Los Angeles Latino Eye Study (LALES). is a population-based study of eye disease among Latinos aged 40 or more years. Complete ophthalmic examinations included stereoscopic fundus photography. Masked photographic grading was used to identify and classify ERMs as cellophane macular reflex (CMR) without retinal folds or preretinal macular fibrosis (PMF) with folds. RESULTS. Of the 6142 persons examined at the clinic, 5982 (97%) had gradable retinal photographs. The mean age of the participants was 54.7 +/- 10.7 years; 58% were women. ERMs were present in 18.5% (95% confidence interval [CI]: 17.5%-19.5%) of the participants. Of the participants with ERMs, 19.9% had bilateral ERMs. The prevalence of ERMs increased from 10.1% in persons 40 to 49 years of age to 35.7% in those aged 70 to 79 years and was 22.5% in persons aged 80 years or more. The prevalence was similar in men and women. CMR was present in 16.3% (95% CI: 15.3%-17.2%) and PMF in 2.2% (95% CI: 1.9%-2.6%). Retinal folds involved the fovea in 11% of PMF cases. On average, eyes with central PMF had poorer visual acuity than did eyes without (P < 0.0002). Epiretinal membranes (ERMs) were present in 71% of eyes with macular holes. ERMs were also more common in individuals who had undergone cataract surgery (39.9%), those with proliferative diabetic retinopathy (25.7%), and those with any retinal disease (27.5%). CONCLUSIONS. ERMs occur frequently in Latinos, often bilaterally. The associations of ERMs with proliferative retinopathy, retinal lesions, macular holes, and cataract surgery were confirmed. Central PMF is associated with reduced visual acuity.
引用
收藏
页码:1732 / 1736
页数:5
相关论文
共 26 条
[1]  
Anand R, 2002, RETINA-J RET VIT DIS, V22, P779
[2]   SECONDARY CAUSES OF PREMACULAR FIBROSIS [J].
APPIAH, AP ;
HIROSE, T .
OPHTHALMOLOGY, 1989, 96 (03) :389-392
[3]   Sine Amsler Charts: a new method for the follow-up of metamorphopsia in patients undergoing macular pucker surgery [J].
Bouwens, MD ;
Meurs, JC .
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2003, 241 (02) :89-93
[4]   LENS OPACITIES CLASSIFICATION SYSTEM-II (LOCS-II) [J].
CHYLACK, LT ;
LESKE, MC ;
MCCARTHY, D ;
KHU, P ;
KASHIWAGI, T ;
SPERDUTO, R .
ARCHIVES OF OPHTHALMOLOGY, 1989, 107 (07) :991-997
[5]  
Ciulla TA, 1997, OPHTHALMIC SURG LAS, V28, P670
[6]   NEW VISUAL-ACUITY CHARTS FOR CLINICAL RESEARCH [J].
FERRIS, FL ;
KASSOFF, A ;
BRESNICK, GH ;
BAILEY, I .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1982, 94 (01) :91-96
[7]   Five-year cumulative incidence and progression of epiretinal membranes - The Blue Mountains Eye Study [J].
Fraser-Bell, S ;
Guzowski, M ;
Rochtchina, E ;
Wang, JJ ;
Mitchell, P .
OPHTHALMOLOGY, 2003, 110 (01) :34-40
[8]   COURSE OF VITREOMACULAR TRACTION SYNDROME [J].
HIKICHI, T ;
YOSHIDA, A ;
TREMPE, CL .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1995, 119 (01) :55-61
[9]   ROLE OF THE VITREOUS IN IDIOPATHIC PRERETINAL MACULAR FIBROSIS [J].
HIROKAWA, H ;
JALKH, AE ;
TAKAHASHI, M ;
TAKAHASHI, M ;
TREMPE, CL ;
SCHEPENS, CL .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1986, 101 (02) :166-169
[10]   RETINAL AND EPIRETINAL GLIA - AN IMMUNOHISTOCHEMICAL STUDY [J].
HISCOTT, PS ;
GRIERSON, I ;
TROMBETTA, CJ ;
RAHI, AHS ;
MARSHALL, J ;
MCLEOD, D .
BRITISH JOURNAL OF OPHTHALMOLOGY, 1984, 68 (10) :698-707