Solid-phase synthesis of functionalized 1,2,3-triazoles

被引：21

作者：

Blass, BE ^{[1
]}

Coburn, KR ^{[1
]}

Faulkner, AL ^{[1
]}

Hunn, CL ^{[1
]}

Natchus, MG ^{[1
]}

Parker, MS ^{[1
]}

Portlock, DE ^{[1
]}

Tullis, JS ^{[1
]}

Wood, R ^{[1
]}

机构：

[1] Procter & Gamble Pharmaceut, Hlth Care Res Ctr, Mason, OH 45040 USA

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(02)00742-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Functionalized 1,2,3-triazoles are prepared by 2+3 cycloaddition of resin bound a-azido esters with substituted alkynes. The reaction is regioselective when the electron-deficient alkyne methyl propiolate is used. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：4059 / 4061

页数：3

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