Spirostanol pentaglycosides from the underground parts of Polianthes tuberosa

被引：11

作者：

Mimaki, Y

Yokosuka, A

Sakuma, C

Sakagami, H

Sashida, Y

机构：

[1] Tokyo Univ Pharm & Life Sci, Sch Pharm, Tokyo 1920392, Japan

[2] Meikai Univ, Sch Dent, Dept Dent Pharmacol, Sakado, Saitama 3500283, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 10期

关键词：

D O I：

10.1021/np020133t

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytochemical analysis of the underground parts of Polianthes tuberosa has resulted in the isolation of four new spirostanol saponins with five monosaccharides (1-4). Their structures were determined by spectroscopic analysis, including extensive 1D and 2D NMR data, and the results of hydrolytic cleavage. The cytotoxic activities of 1-4 against HL-60 human promyelocytic leukemia cells and HSC-2 human oral squamous cell carcinoma cells are reported.

引用

页码：1424 / 1428

页数：5

共 16 条

[1] NMR-SPECTROSCOPY IN THE STRUCTURAL ELUCIDATION OF OLIGOSACCHARIDES AND GLYCOSIDES [J].