CTLA-4: a key protein in autoimmunity

被引：23

作者：

Bayry, Jagadeesh ^{[1
]}

机构：

[1] Ctr Rech Cordeliers, Equipe 16, INSERM, U872, F-75006 Paris, France

来源：

NATURE REVIEWS RHEUMATOLOGY | 2009年 / 5卷 / 05期

关键词：

REGULATORY T-CELLS; RHEUMATOID-ARTHRITIS;

D O I：

10.1038/nrrheum.2009.77

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Studies performed during the past 2 years have provided a deeper understanding into the role of CTLA-4, which is expressed on regulatory T cells, in preventing autoimmunity, and also provide mechanistic insight into protein-based therapeutics such as abatacept for rheumatic diseases.

引用

页码：244 / 245

页数：3

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