Applicability of staging systems for patients with hepatocellular carcinoma is dependent on treatment method - Analysis of 2010 Taiwanese patients

被引：65

作者：

Chen, Chien-Hung ^{[1
,2
]}

Hu, Fu-Chang ^{[3
,10
]}

Huang, Guan-Tarn ^{[1
,2
]}

Lee, Po-Huang ^{[4
]}

Tsang, Yuk-Ming ^{[5
]}

Cheng, Ann-Lii ^{[1
,2
,6
]}

Chen, Ding-Shinn ^{[1
,2
,7
,8
]}

Wang, Jung-Der ^{[1
,2
,9
]}

Sheu, Jin-Chuan ^{[1
,2
]}

机构：

[1] Natl Taiwan Univ Hosp, Dept Internal Med, Taipei 10016, Taiwan

[2] Natl Taiwan Univ, Coll Med, Taipei 10016, Taiwan

[3] Natl Taiwan Univ Hosp, Dept Med Res, Taipei 10016, Taiwan

[4] Natl Taiwan Univ Hosp, Dept Surg, Taipei 10016, Taiwan

[5] Natl Taiwan Univ Hosp, Dept Med Imaging, Taipei 10016, Taiwan

[6] Natl Taiwan Univ Hosp, Dept Oncol, Taipei 10016, Taiwan

[7] Natl Taiwan Univ Hosp, Grad Inst Clin Med, Taipei 10016, Taiwan

[8] Natl Taiwan Univ Hosp, Hepatitis Res Ctr, Taipei 10016, Taiwan

[9] Natl Taiwan Univ, Inst Occupat Med & Ind Hyg, Coll Publ Hlth, Taipei 10764, Taiwan

[10] Natl Taiwan Univ Hosp, Stat Consulting Clin, Natl Ctr Excellence Gen Clin Trial & Res, Taipei 10016, Taiwan

来源：

EUROPEAN JOURNAL OF CANCER | 2009年 / 45卷 / 09期

关键词：

Hepatocellular carcinoma; Staging; Scoring; Prognosis; Taiwan; LIVER-ITALIAN-PROGRAM; PROGNOSTIC CLASSIFICATION; PREDICTING SURVIVAL; CLIP SCORE; CANCER; OKUDA; BCLC; JIS; VALIDATION; HEPATECTOMY;

D O I：

10.1016/j.ejca.2008.12.025

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The aim of this study was to compare six prognostic staging systems (Okuda stage, TNM stage, CLIP score, BCLC stage, JIS score and Tokyo score) in predicting survival in patients with hepatocellular carcinoma (HCC). A total of 2010 Taiwanese HCC patients were included. Demographic, laboratory and tumour characteristics were determined at diagnosis. Predictors of survival included serum levels of albumin, total bilirubin, alkaline phosphatase, alpha-fetoprotein, ascites, tumour size and portal vein invasion. The Tokyo score was the most informative one for predicting the survival of HCC patients as a whole, receiving surgical resection, or receiving transarterial chemoembolisation. CLIP score was the best fit system for HCC patients receiving chemotherapy or supportive care. Each staging system showed a significant difference in predicting the probability of survival across different stages. The applicability of staging systems for patients with HCC was dependent on treatment methods. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：1630 / 1639

页数：10

共 48 条

[1] Treatment of hepatocellular carcinoma [J].

Blum, HE .

BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY, 2005, 19 (01) :129-145

[2] Management of hepatoceullular carcinoma [J].

Bruix, J ;

Sherman, M .

HEPATOLOGY, 2005, 42 (05) :1208-1236

[3] Survival of patients with hepatocellular carcinoma in cirrhosis:: a comparison of BCLC, CLIP and GRETCH staging systems [J].

Camma, C. ;

Di Marco, V. ;

Cabibbo, G. ;

Latteri, F. ;

Sandonato, L. ;

Parisi, P. ;

Enea, M. ;

Attanasio, M. ;

Galia, M. ;

Alessi, N. ;

Licata, A. ;

Latteri, M. A. ;

Craxi, A. .

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2008, 28 (01) :62-75

[4]

Chen C.-H., 1992, Journal of the Formosan Medical Association, V91, pS187

[5] Comparison of clinical staging systems in predicting survival of hepatocellular carcinoma patients receiving major or minor hepatectomy [J].

Chen, T. W. ;

Chu, C. M. ;

Yu, J. C. ;

Chen, C. J. ;

Chan, D. C. ;

Liu, Y. C. ;

Hsieh, C. B. .

EJSO, 2007, 33 (04) :480-487

[6] A new prognostic classification for predicting survival in patients with hepatocellular carcinoma [J].

Chevret, S ;

Trinchet, JC ;

Mathieu, D ;

Rached, AA ;

Beaugrand, M ;

Chastang, C .

JOURNAL OF HEPATOLOGY, 1999, 31 (01) :133-141

[7]

CHO YK, 2008, CANCER, V23, P1874

[8] Comparison of three current staging systems for hepatocellular carcinoma: Japan integrated staging score, new Barcelona Clinic Liver Cancer staging classification, and Tokyo score [J].

Chung, Hobyung ;

Kudo, Masatoshi ;

Takahashi, Shunsuke ;

Hagiwara, Satoru ;

Sakaguchi, Yasuhiro ;

Inoue, Tatsuo ;

Minami, Yasunori ;

Ueshima, Kazuomi ;

Fukunaga, Toyokazu ;

Matsunaga, Takashi .

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2008, 23 (03) :445-452

[9] Prospective validation of the Barcelona Clinic Liver Cancer staging system [J].

Cillo, U ;

Vitale, A ;

Grigoletto, F ;

Farinati, F ;

Brolese, A ;

Zanus, G ;

Neri, D ;

Boccagni, P ;

Srsen, N ;

D'Amico, F ;

Ciarleglio, FA ;

Bridda, A ;

D'Amico, DF .

JOURNAL OF HEPATOLOGY, 2006, 44 (04) :723-731

[10] The critical issue of hepatocellular carcinoma prognostic classification: which is the best tool available? [J].

Cillo, U ;

Bassanello, M ;

Vitale, A ;

Grigoletto, FA ;

Burra, P ;

Fagiuoli, S ;

D'Amico, F ;

Ciarleglio, FA ;

Boccagni, P ;

Brolese, A ;

Zanus, G ;

D'Amico, DF .

JOURNAL OF HEPATOLOGY, 2004, 40 (01) :124-131

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