Inflammation, brain damage and visual dysfunction in preterm infants

被引:58
作者
Dammann, Olaf
Leviton, Alan
机构
[1] Hannover Med Sch, Perinatal Infect Dis Epidemiol Unit, Dept Gynecol & Obstet, D-30623 Hannover, Germany
[2] Hannover Med Sch, Dept Pediat Pulm & Neonatol, D-30623 Hannover, Germany
[3] Childrens Hosp, Dept Neurol, Neuroepidemiol Unit, Boston, MA 02215 USA
[4] Harvard Univ, Sch Med, Boston, MA 02215 USA
关键词
inflammation; brain; vision; infant; premature;
D O I
10.1016/j.siny.2006.02.003
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Antenatal intrauterine infection and the fetal inflammatory response appear to be important pathogenetic factors in preterm birth and subsequent neonatal disorders of the lung and brain. In this paper, we expand this concept to include visual dysfunction. Although present data tend to support our notion, we suggest that more experimental and epidemiological research is needed to elucidate mechanisms of infection/inflammation-induced damage to the eye and visual brain pathways of preterm infants. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码:363 / 368
页数:6
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