Identification of deoxymiroestrol as the actual rejuvenating principle of "Kwao Keur", Pueraria mirifica.: The known miroestrol may be an artifact

被引：126

作者：

Chansakaow, S

Ishikawa, T

Seki, H

Sekine, K

Okada, M

Chaichantipyuth, C

机构：

[1] Chiba Univ, Fac Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan

[2] Chiba Univ, Ctr Chem Anal, Inage Ku, Chiba 2638522, Japan

[3] Nippon Kayaku Co Ltd, R&D Div, Kita Ku, Tokyo 1158588, Japan

[4] Chulalongkorn Univ, Fac Pharmaceut Sci, Dept Pharmacognosy, Bangkok 10330, Thailand

来源：

JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 02期

关键词：

D O I：

10.1021/np990547v

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Miroestrol (1) has been isolated previously as an active principle from "Kwao Keur" (Pueraria mirifica), a rejuvenating folk medicine from Thailand. Reinvestigation using bioassay-guided purification has resulted in the isolation of a new potent phytoestrogen, deoxymiroestrol (2). The facile aerial oxidation of 2 into 1 suggests the possibility that 1 may be an artifact.

引用

页码：173 / 175

页数：3

共 13 条

[1]

LIGHT-ABSORPTION AND CHEMICAL PROPERTIES OF MIROESTROL, THE OESTROGENIC SUBSTANCE OF PUERARIA-MIRIFICA [J].