Gamma Knife radiosurgery for pituitary adenomas

被引:74
作者
Hayashi, M [1 ]
Izawa, M [1 ]
Hiyama, H [1 ]
Nakamura, S [1 ]
Atsuchi, S [1 ]
Sato, H [1 ]
Nakaya, K [1 ]
Sasaki, K [1 ]
Ochiai, T [1 ]
Kubo, O [1 ]
Hori, T [1 ]
Takakura, K [1 ]
机构
[1] Tokyo Womens Med Univ, Neurol Inst, Dept Neurosurg, Shinjuku Ku, Tokyo 1628666, Japan
关键词
Gamma Knife; radiosurgery; pituitary adenomas; radiation complication; endocrinopathy;
D O I
10.1159/000056446
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Ninety-two patients with pituitary adenomas have been treated during the last 5 years. Sixty-three of these patients had more than 6 months follow-up, and they form the basis of this report. Eighteen had non-functioning adenomas (NFA), and 36 had functioning adenomas (FA). The mean marginal dose was 22.5 Gy (NFA 19.5 Gy, FA 23.9 Gy). Control of tumor growth was achieved in 92%. A significant decrease of excessive hormone production was seen in 75.6%, and the endocrinopathy normalization rate was 26.7%. Post-radiosurgical complications were seen in 4.7%. Copyright (C) 1999 S. Karger AG, Basel.
引用
收藏
页码:111 / 118
页数:8
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